Claudin-1 decrease impacts epidermal barrier function in atopic dermatitis lesions dose-dependently

The transmembrane protein claudin-1 is a major component of epidermal tight junctions (TJs), which create a dynamic paracellular barrier in the epidermis. Claudin-1 downregulation has been linked to atopic dermatitis (AD) pathogenesis but variable levels of claudin-1 have also been observed in healt...

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Detalles Bibliográficos
Autores principales: Bergmann, Sophia, von Buenau, Barbara, Vidal-y-Sy, Sabine, Haftek, Marek, Wladykowski, Ewa, Houdek, Pia, Lezius, Susanne, Duplan, Hélène, Bäsler, Katja, Dähnhardt-Pfeiffer, Stephan, Gorzelanny, Christian, Schneider, Stefan W., Rodriguez, Elke, Stölzl, Dora, Weidinger, Stephan, Brandner, Johanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004991/
https://www.ncbi.nlm.nih.gov/pubmed/32029783
http://dx.doi.org/10.1038/s41598-020-58718-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004991/
https://www.ncbi.nlm.nih.gov/pubmed/32029783
http://dx.doi.org/10.1038/s41598-020-58718-9

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