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Formate dehydrogenase, ubiquinone, and cytochrome bd-I are required for peptidoglycan recognition protein-induced oxidative stress and killing in Escherichia coli

Mammalian Peptidoglycan Recognition Proteins (PGRPs) kill bacteria through induction of synergistic oxidative, thiol, and metal stress. PGRPs induce oxidative stress in bacteria through a block in the respiratory chain, which results in decreased respiration and incomplete reduction of oxygen (O(2))...

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Detalles Bibliográficos
Autores principales: Kashyap, Des R., Kowalczyk, Dominik A., Shan, Yue, Yang, Chun-Kai, Gupta, Dipika, Dziarski, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005000/
https://www.ncbi.nlm.nih.gov/pubmed/32029761
http://dx.doi.org/10.1038/s41598-020-58302-1