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A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes

Crosslinking-mass spectrometry (XL-MS) serves to identify interaction sites between proteins. Numerous search engines for crosslink identification exist, but lack of ground truth samples containing known crosslinks has precluded their systematic validation. Here we report on XL-MS data arising from...

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Detalles Bibliográficos
Autores principales: Beveridge, Rebecca, Stadlmann, Johannes, Penninger, Josef M., Mechtler, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005041/
https://www.ncbi.nlm.nih.gov/pubmed/32029734
http://dx.doi.org/10.1038/s41467-020-14608-2