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Fasting induces remodeling of the orexigenic projections from the arcuate nucleus to the hypothalamic paraventricular nucleus, in a growth hormone secretagogue receptor–dependent manner

OBJECTIVE: Arcuate nucleus (ARC) neurons producing Agouti-related peptide (AgRP) and neuropeptide Y (NPY; ARC(AgRP/NPY) neurons) are activated under energy-deficit states. ARC(AgRP/NPY) neurons innervate the hypothalamic paraventricular nucleus (PVH), and ARC→PVH projections are recognized as key re...

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Detalles Bibliográficos
Autores principales: Cabral, Agustina, Fernandez, Gimena, Tolosa, María J., Rey Moggia, Ángeles, Calfa, Gastón, De Francesco, Pablo N., Perello, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005150/
https://www.ncbi.nlm.nih.gov/pubmed/32029231
http://dx.doi.org/10.1016/j.molmet.2019.11.014