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Hepatocyte caveolin-1 modulates metabolic gene profiles and functions in non-alcoholic fatty liver disease

Caveolin-1 (CAV1) is a crucial regulator of lipid accumulation and metabolism. Previous studies have shown that global Cav1 deficiency affects lipid metabolism and hepatic steatosis. We aimed to analyze the consequences of hepatocyte-specific Cav1 knockout under healthy conditions and upon non-alcoh...

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Detalles Bibliográficos
Autores principales: Han, Mei, Piorońska, Weronika, Wang, Sai, Nwosu, Zeribe Chike, Sticht, Carsten, Wang, Shanshan, Gao, Yan, Ebert, Matthias Philip, Dooley, Steven, Meyer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005160/
https://www.ncbi.nlm.nih.gov/pubmed/32029710
http://dx.doi.org/10.1038/s41419-020-2295-5