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Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions

Accurate quantification of heartbeats in fish models is an important readout to study cardiovascular biology, disease states and pharmacology. However, dependence on anaesthesia, laborious sample orientation or requirement for fluorescent reporters have hampered the use of high-throughput heartbeat...

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Detalles Bibliográficos
Autores principales: Gierten, Jakob, Pylatiuk, Christian, Hammouda, Omar T., Schock, Christian, Stegmaier, Johannes, Wittbrodt, Joachim, Gehrig, Jochen, Loosli, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005164/
https://www.ncbi.nlm.nih.gov/pubmed/32029752
http://dx.doi.org/10.1038/s41598-020-58563-w