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Holographic molecular binding assays

We demonstrate that holographic particle characterization can directly detect binding of proteins to functionalized colloidal probe particles by monitoring the associated change in the particles’ size. This label-free molecular binding assay uses in-line holographic video microscopy to measure the d...

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Detalles Bibliográficos
Autores principales: Zagzag, Yvonne, Soddu, M. Francesca, Hollingsworth, Andrew D., Grier, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005168/
https://www.ncbi.nlm.nih.gov/pubmed/32029807
http://dx.doi.org/10.1038/s41598-020-58833-7