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A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 is highly metastatic in vivo

Despite recent advances in melanoma treatment, metastasis and resistance to therapy remain serious clinical challenges. NME1 is a metastasis suppressor, a class of proteins which inhibits metastatic spread of cancer cells without impact on growth of the primary tumor. We have identified a rare subpo...

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Detalles Bibliográficos
Autores principales: Snyder, Devin, Wang, Ying, Kaetzel, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005181/
https://www.ncbi.nlm.nih.gov/pubmed/32029850
http://dx.doi.org/10.1038/s41598-020-58996-3