A combined Far-FTIR, FTIR Spectromicroscopy, and DFT Study of the Effect of DNA Binding on the [4Fe4S] Cluster Site in EndoIII

Endonuclease III (EndoIII) is a DNA glycosylase that contains the [4Fe4S] cluster, which is essential for the protein to bind to damaged DNA in a process called base excision repair (BER). Here we propose that the change in the covalency of Fe–S bonds of the [4Fe4S] cluster caused by double-stranded...

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Detalles Bibliográficos
Autores principales: Hassan, Ayaz, Macedo, Lucyano J. A., Souza, João C. P. de, Lima, Filipe C. D. A., Crespilho, Frank N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005299/
https://www.ncbi.nlm.nih.gov/pubmed/32029762
http://dx.doi.org/10.1038/s41598-020-58531-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005299/
https://www.ncbi.nlm.nih.gov/pubmed/32029762
http://dx.doi.org/10.1038/s41598-020-58531-4

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