Functional dynamics of a single tryptophan residue in a BLUF protein revealed by fluorescence spectroscopy

Blue Light Using Flavin (BLUF) domains are increasingly being adopted for use in optogenetic constructs. Despite this, much remains to be resolved on the mechanism of their activation. The advent of unnatural amino acid mutagenesis opens up a new toolbox for the study of protein structural dynamics....

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Detalles Bibliográficos
Autores principales: Karadi, Kristof, Kapetanaki, Sofia M., Raics, Katalin, Pecsi, Ildiko, Kapronczai, Robert, Fekete, Zsuzsanna, Iuliano, James N., Collado, Jinnette Tolentino, Gil, Agnieszka A., Orban, Jozsef, Nyitrai, Miklos, Greetham, Greg M., Vos, Marten H., Tonge, Peter J., Meech, Stephen R., Lukacs, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005313/
https://www.ncbi.nlm.nih.gov/pubmed/32029866
http://dx.doi.org/10.1038/s41598-020-59073-5

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