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Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
Rheumatoid arthritis affects individuals commonly during the most productive years of adulthood. Poor response rates and high costs associated with treatment mandate the search for new therapies. Here we show that targeting a specific G-protein coupled receptor promotes senescence in synovial fibrob...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005314/ https://www.ncbi.nlm.nih.gov/pubmed/32029712 http://dx.doi.org/10.1038/s41467-020-14421-x |