The urotensin II receptor antagonist DS37001789 ameliorates mortality in pressure-overload mice with heart failure

This study was designed to evaluate the effects of DS37001789, a novel and highly potent urotensin II (U-II) receptor (GPR14) antagonist, against mortality, hypertrophy, and cardiac dysfunction in pressure-overload hypertrophy by transverse aortic constriction (TAC) in mice. In addition, we analyzed...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishi, Mina, Tagawa, Hideki, Ueno, Masumi, Marumoto, Shinji, Nagayama, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005433/
https://www.ncbi.nlm.nih.gov/pubmed/32055741
http://dx.doi.org/10.1016/j.heliyon.2020.e03352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005433/
https://www.ncbi.nlm.nih.gov/pubmed/32055741
http://dx.doi.org/10.1016/j.heliyon.2020.e03352

Ejemplares similares