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Durable therapeutic gain despite competing mortality in long-term follow-up of a randomized hyperfractionated radiotherapy trial for locally advanced head and neck cancer

PURPOSE/OBJECTIVE(S): To examine the therapeutic ratio and mortality profile over time in a radiotherapy randomized trial in stage III-IV larynx/pharynx cancer with long-term follow-up. MATERIALS/METHODS: From 1988 to 1995, 331 cases were randomized to either hyperfractionated (HF) (58 Gy/40 fractio...

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Detalles Bibliográficos
Autores principales: O'Sullivan, Brian, Hui Huang, Shao, Keane, Thomas, Xu, Wei, Su, Jie, Waldron, John, Gullane, Patrick, Liu, Fei-Fei, Warde, Padraig, Payne, David, Tong, Li, Cummings, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005479/
https://www.ncbi.nlm.nih.gov/pubmed/32055717
http://dx.doi.org/10.1016/j.ctro.2020.01.003