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Wnt7a Counteracts Cancer Cachexia

Cancer cachexia is a complex metabolic disease so far lacking effective therapy, and it accounts for approximately one third of all cancer-related deaths worldwide. The extracellular ligand Wnt7a has a dual function in skeletal muscle, inducing the anabolic AKT/mammalian target of rapamycin (mTOR) p...

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Detalles Bibliográficos
Autores principales: Schmidt, Manuel, Poser, Christine, von Maltzahn, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005483/
https://www.ncbi.nlm.nih.gov/pubmed/32055677
http://dx.doi.org/10.1016/j.omto.2019.12.011