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ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response
The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005498/ https://www.ncbi.nlm.nih.gov/pubmed/32058971 http://dx.doi.org/10.1016/j.isci.2020.100860 |