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ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

The unfolded protein response (UPR) pathway senses unfolded proteins and regulates proteostasis and cell fate through activity of the transcription factors ATF4, ATF6, and XBP1 within a complex network of three main branches. Here, we investigated contributions of the three branches to UPR activity...

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Detalles Bibliográficos
Autores principales:	Yang, Huan, Niemeijer, Marije, van de Water, Bob, Beltman, Joost B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005498/ https://www.ncbi.nlm.nih.gov/pubmed/32058971 http://dx.doi.org/10.1016/j.isci.2020.100860

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