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Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus

Systemic lupus erythematosus (SLE) is characterized by high levels of autoantibodies and multiorgan tissue damage. The pathogenesis of splenomegaly in SLE remains unknown. In this study, the role of immunoglobulin G (IgG) generation and deposition in the inflammation of the spleen and associated dys...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Xiang, Liping, Zaman, Muhammad Haidar, Dong, Wenhui, He, Guodan, Deng, Guo-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005523/
https://www.ncbi.nlm.nih.gov/pubmed/32082297
http://dx.doi.org/10.3389/fimmu.2019.03020