A selective androgen receptor modulator SARM‐2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys

SARM‐2f a selective androgen receptor (AR) modulator, increases skeletal muscle mass and locomotor activity in rats. This study aimed to clarify its pharmacological effects in monkeys. In reporter assays, the EC(50) values of SARM‐2f for rat, monkey, and human AR were 2.5, 3, and 3.6 nmol/L, respect...

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Detalles Bibliográficos
Autores principales: Morimoto, Megumi, Yamaoka, Masuo, Hara, Takahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005530/
https://www.ncbi.nlm.nih.gov/pubmed/32030892
http://dx.doi.org/10.1002/prp2.563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005530/
https://www.ncbi.nlm.nih.gov/pubmed/32030892
http://dx.doi.org/10.1002/prp2.563

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