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Endothelial MT1‐MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis

Pathological angiogenesis contributes to cancer progression and chronic inflammatory diseases. In inflammatory bowel disease, the microvasculature expands by intussusceptive angiogenesis (IA), a poorly characterized mechanism involving increased blood flow and splitting of pre‐existing capillaries....

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Detalles Bibliográficos
Autores principales: Esteban, Sergio, Clemente, Cristina, Koziol, Agnieszka, Gonzalo, Pilar, Rius, Cristina, Martínez, Fernando, Linares, Pablo M, Chaparro, María, Urzainqui, Ana, Andrés, Vicente, Seiki, Motoharu, Gisbert, Javier P, Arroyo, Alicia G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005619/
https://www.ncbi.nlm.nih.gov/pubmed/31793743
http://dx.doi.org/10.15252/emmm.201910862