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Intrahepatic macrophage populations in the pathophysiology of primary sclerosing cholangitis

BACKGROUND & AIMS: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammatory and fibrotic injury to the biliary tree. We sought to further delineate the contribution of macrophage lineages in PSC pathobiology. METHODS: Human liver tissu...

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Detalles Bibliográficos
Autores principales: Chen, Yung-Yi, Arndtz, Kathryn, Webb, Gwilym, Corrigan, Margaret, Akiror, Sarah, Liaskou, Evaggelia, Woodward, Paul, Adams, David H., Weston, Chris J., Hirschfield, Gideon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005651/
https://www.ncbi.nlm.nih.gov/pubmed/32039388
http://dx.doi.org/10.1016/j.jhepr.2019.10.003