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Using CRISPR/Cas9 to model human liver disease

CRISPR/Cas9 gene editing has revolutionised biomedical research. The ease of design has allowed many groups to apply this technology for disease modelling in animals. While the mouse remains the most commonly used organism for embryonic editing, CRISPR is now increasingly performed with high efficie...

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Detalles Bibliográficos
Autores principales: Alves-Bezerra, Michele, Furey, Nika, Johnson, Collin G., Bissig, Karl-Dimiter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005665/
https://www.ncbi.nlm.nih.gov/pubmed/32039390
http://dx.doi.org/10.1016/j.jhepr.2019.09.002