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Quetiapine Modulates Histone Methylation Status in Oligodendroglia and Rescues Adolescent Behavioral Alterations of Socially Isolated Mice

Epigenetic alterations and impaired oligodendroglial myelination in the prefrontal cortex have been shown to correlate with behavioral and cognitive dysfunctions in social deprivation. Our previous study demonstrated that quetiapine, an atypical antipsychotic, could promote oligodendroglial differen...

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Detalles Bibliográficos
Autores principales: Chen, Xianjun, Liu, Hao, Gan, Jingli, Wang, Xiaorui, Yu, Guangdan, Li, Tao, Liang, Xuejun, Yu, Bin, Xiao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005666/
https://www.ncbi.nlm.nih.gov/pubmed/32082195
http://dx.doi.org/10.3389/fpsyt.2019.00984