IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

Our understanding of the signalling pathways regulating early human development is limited, despite their fundamental biological importance. Here, we mine transcriptomics datasets to investigate signalling in the human embryo and identify expression for the insulin and insulin growth factor 1 (IGF1)...

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Detalles Bibliográficos
Autores principales: Wamaitha, Sissy E., Grybel, Katarzyna J., Alanis-Lobato, Gregorio, Gerri, Claudia, Ogushi, Sugako, McCarthy, Afshan, Mahadevaiah, Shantha K., Healy, Lyn, Lea, Rebecca A., Molina-Arcas, Miriam, Devito, Liani G., Elder, Kay, Snell, Phil, Christie, Leila, Downward, Julian, Turner, James M. A., Niakan, Kathy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005693/
https://www.ncbi.nlm.nih.gov/pubmed/32034154
http://dx.doi.org/10.1038/s41467-020-14629-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005693/
https://www.ncbi.nlm.nih.gov/pubmed/32034154
http://dx.doi.org/10.1038/s41467-020-14629-x

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