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Validation of a novel and accurate ApoE4 assay for automated chemistry analyzers

The allele ε4 of the apolipoprotein E gene (APOE ε4) is the major genetic risk factor for non-dominantly inherited Alzheimer’s Disease (AD). Current techniques for APOE ε4 carriers identification show good accuracy but have several disadvantages that limit its implementation in a clinical laboratory...

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Detalles Bibliográficos
Autores principales: Veiga, Sergio, Rodríguez-Martín, Andrés, Garcia-Ribas, Guillermo, Arribas, Ignacio, Menacho-Román, Miriam, Calero, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005722/
https://www.ncbi.nlm.nih.gov/pubmed/32034174
http://dx.doi.org/10.1038/s41598-020-58841-7