MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments

Human Ebp1 is a member of the proliferation-associated 2G4 (PA2G4) family and plays an important role in cancer regulation. Ebp1 shares the methionine aminopeptidase (MetAP) fold and binds to mature 80S ribosomes for translational control. Here, we present a cryo-EM single particle analysis reconstr...

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Detalles Bibliográficos
Autores principales: Wild, Klemens, Aleksić, Milan, Lapouge, Karine, Juaire, Keven D., Flemming, Dirk, Pfeffer, Stefan, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005732/
https://www.ncbi.nlm.nih.gov/pubmed/32034140
http://dx.doi.org/10.1038/s41467-020-14603-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005732/
https://www.ncbi.nlm.nih.gov/pubmed/32034140
http://dx.doi.org/10.1038/s41467-020-14603-7

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