C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition

Extracellular signals such as TGF-β can induce epithelial-to-mesenchymal transition (EMT) in cancers of epithelial origin, promoting molecular and phenotypical changes resulting in pro-metastatic characteristics. We identified C/EBPα as one of the most TGF-β-mediated downregulated transcription fact...

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Detalles Bibliográficos
Autores principales: Lourenço, Ana Rita, Roukens, M. Guy, Seinstra, Danielle, Frederiks, Cynthia L., Pals, Cornelieke E., Vervoort, Stephin J., Margarido, Andreia S., van Rheenen, Jacco, Coffer, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005738/
https://www.ncbi.nlm.nih.gov/pubmed/32034145
http://dx.doi.org/10.1038/s41467-020-14556-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005738/
https://www.ncbi.nlm.nih.gov/pubmed/32034145
http://dx.doi.org/10.1038/s41467-020-14556-x

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