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Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

The fatty acid translocase, also known as CD36, is a well-established scavenger receptor for fatty acid (FA) uptake and is abundantly expressed in many metabolically active tissues. In the liver, CD36 is known to contribute to the progression of non-alcoholic fatty liver disease and to the more seve...

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Detalles Bibliográficos
Autores principales: Lebeau, Paul F., Byun, Jae Hyun, Platko, Khrystyna, Al-Hashimi, Ali A., Lhoták, Šárka, MacDonald, Melissa E., Mejia-Benitez, Aurora, Prat, Annik, Igdoura, Suleiman A., Trigatti, Bernardo, Maclean, Kenneth N., Seidah, Nabil G., Austin, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005770/
https://www.ncbi.nlm.nih.gov/pubmed/32039393
http://dx.doi.org/10.1016/j.jhepr.2019.10.009