De novo strategy with engineering anti-Kasha/Kasha fluorophores enables reliable ratiometric quantification of biomolecules

Fluorescence-based technologies have revolutionized in vivo monitoring of biomolecules. However, significant technical hurdles in both probe chemistry and complex cellular environments have limited the accuracy of quantifying these biomolecules. Herein, we report a generalizable engineering strategy...

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Detalles Bibliográficos
Autores principales: Shi, Limin, Yan, Chenxu, Guo, Zhiqian, Chi, Weijie, Wei, Jingle, Liu, Weimin, Liu, Xiaogang, Tian, He, Zhu, Wei-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005775/
https://www.ncbi.nlm.nih.gov/pubmed/32034152
http://dx.doi.org/10.1038/s41467-020-14615-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005775/
https://www.ncbi.nlm.nih.gov/pubmed/32034152
http://dx.doi.org/10.1038/s41467-020-14615-3

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