Quantifying Hematopoietic Stem Cell Clonal Diversity by Selecting Informative Amplicon Barcodes

Hematopoietic stem cells (HSCs) are functionally and genetically diverse and this diversity decreases with age and disease. Numerous systems have been developed to quantify HSC diversity by genetic barcoding, but no framework has been established to empirically validate barcode sequences. Here we ha...

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Detalles Bibliográficos
Autores principales: Teets, Emily M., Gregory, Charles, Shaffer, Jami, Blachly, James S., Blaser, Bradley W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005852/
https://www.ncbi.nlm.nih.gov/pubmed/32034234
http://dx.doi.org/10.1038/s41598-020-59119-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005852/
https://www.ncbi.nlm.nih.gov/pubmed/32034234
http://dx.doi.org/10.1038/s41598-020-59119-8

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