CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide

Multiple myeloma (MM) is a plasma cell malignancy and most patients eventually succumb to the disease. Chimeric antigen receptor (CAR) T cells targeting B-Cell Maturation Antigen (BCMA) on MM cells have shown high-response rates, but limited durability. CD229/LY9 is a cell surface receptor present o...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Sabarinath V., Luetkens, Tim, Scherer, Sandra D., Davis, Patricia, Vander Mause, Erica R., Olson, Michael L., Yousef, Sara, Panse, Jens, Abdiche, Yasmina, Li, K. David, Miles, Rodney R., Matsui, William, Welm, Alana L., Atanackovic, Djordje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005855/
https://www.ncbi.nlm.nih.gov/pubmed/32034142
http://dx.doi.org/10.1038/s41467-020-14619-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005855/
https://www.ncbi.nlm.nih.gov/pubmed/32034142
http://dx.doi.org/10.1038/s41467-020-14619-z

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