Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries

Quantitative phosphoproteomics has transformed investigations of cell signaling, but it remains challenging to scale the technology for high-throughput analyses. Here we report a rapid and reproducible approach to analyze hundreds of phosphoproteomes using data-independent acquisition (DIA) with an...

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Detalles Bibliográficos
Autores principales: Bekker-Jensen, Dorte B., Bernhardt, Oliver M., Hogrebe, Alexander, Martinez-Val, Ana, Verbeke, Lynn, Gandhi, Tejas, Kelstrup, Christian D., Reiter, Lukas, Olsen, Jesper V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005859/
https://www.ncbi.nlm.nih.gov/pubmed/32034161
http://dx.doi.org/10.1038/s41467-020-14609-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005859/
https://www.ncbi.nlm.nih.gov/pubmed/32034161
http://dx.doi.org/10.1038/s41467-020-14609-1

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