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Establishment of Structure-Function Relationship of Tissue Inhibitor of Metalloproteinase-1 for Its Interaction with CD63: Implication for Cancer Therapy

Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a pleiotropic protein, promoting both tumor-suppressive and tumor-promoting activities. While TIMP-1 is primarily known as an endogenous inhibitor of matrix metalloproteinases (MMPs) and thus associated with tumor cell invasion, clinical studies d...

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Detalles Bibliográficos
Autores principales: Warner, Richard B., Najy, Abdo J., Jung, Young Suk, Fridman, Rafael, Kim, Seongho, Kim, Hyeong-Reh Choi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005868/
https://www.ncbi.nlm.nih.gov/pubmed/32034211
http://dx.doi.org/10.1038/s41598-020-58964-x