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Drug-target interaction prediction with tree-ensemble learning and output space reconstruction
BACKGROUND: Computational prediction of drug-target interactions (DTI) is vital for drug discovery. The experimental identification of interactions between drugs and target proteins is very onerous. Modern technologies have mitigated the problem, leveraging the development of new drugs. However, dru...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006075/ https://www.ncbi.nlm.nih.gov/pubmed/32033537 http://dx.doi.org/10.1186/s12859-020-3379-z |