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Drug-target interaction prediction with tree-ensemble learning and output space reconstruction

BACKGROUND: Computational prediction of drug-target interactions (DTI) is vital for drug discovery. The experimental identification of interactions between drugs and target proteins is very onerous. Modern technologies have mitigated the problem, leveraging the development of new drugs. However, dru...

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Detalles Bibliográficos
Autores principales: Pliakos, Konstantinos, Vens, Celine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006075/
https://www.ncbi.nlm.nih.gov/pubmed/32033537
http://dx.doi.org/10.1186/s12859-020-3379-z