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Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1(+) stem cells from young donors

BACKGROUND: Radiotherapy is widely used and effective for treating brain tumours, but inevitably impairs cognition as it arrests cellular processes important for learning and memory. This is particularly evident in the aged brain with limited regenerative capacity, where radiation produces irreparab...

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Detalles Bibliográficos
Autores principales: Wlodarek, Lukasz, Cao, Feng, Alibhai, Faisal J., Fekete, Adam, Noyan, Nima, Tobin, Stephanie W., Marvasti, Tina B., Wu, Jun, Li, Shu-Hong, Weisel, Richard D., Wang, Lu-Yang, Jia, Zhengping, Li, Ren-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006105/
https://www.ncbi.nlm.nih.gov/pubmed/32028989
http://dx.doi.org/10.1186/s12974-019-1681-3