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Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1(+) stem cells from young donors
BACKGROUND: Radiotherapy is widely used and effective for treating brain tumours, but inevitably impairs cognition as it arrests cellular processes important for learning and memory. This is particularly evident in the aged brain with limited regenerative capacity, where radiation produces irreparab...
Autores principales: | Wlodarek, Lukasz, Cao, Feng, Alibhai, Faisal J., Fekete, Adam, Noyan, Nima, Tobin, Stephanie W., Marvasti, Tina B., Wu, Jun, Li, Shu-Hong, Weisel, Richard D., Wang, Lu-Yang, Jia, Zhengping, Li, Ren-Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006105/ https://www.ncbi.nlm.nih.gov/pubmed/32028989 http://dx.doi.org/10.1186/s12974-019-1681-3 |
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