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The mixed model for repeated measures for cluster randomized trials: a simulation study investigating bias and type I error with missing continuous data

BACKGROUND: Cluster randomized trials (CRTs) are a design used to test interventions where individual randomization is not appropriate. The mixed model for repeated measures (MMRM) is a popular choice for individually randomized trials with longitudinal continuous outcomes. This model’s appeal is du...

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Detalles Bibliográficos
Autores principales: Bell, Melanie L., Rabe, Brooke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006144/
https://www.ncbi.nlm.nih.gov/pubmed/32033617
http://dx.doi.org/10.1186/s13063-020-4114-9