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HIV-1 subtype C predicted co-receptor tropism in Africa: an individual sequence level meta-analysis

BACKGROUND: Entry inhibitors, such as Maraviroc, hold promise as components of HIV treatment and/or pre-exposure prophylaxis in Africa. Maraviroc inhibits the interaction between HIV Envelope gp120 V3-loop and CCR5 coreceptor. HIV-1 subtype C (HIV-1-C) is predominant in Southern Africa and preferabl...

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Detalles Bibliográficos
Autores principales: Matume, Nontokozo D., Tebit, Denis M., Bessong, Pascal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006146/
https://www.ncbi.nlm.nih.gov/pubmed/32033571
http://dx.doi.org/10.1186/s12981-020-0263-x