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Glial remodeling enhances short-term memory performance in Wistar rats

BACKGROUND: Microglia play a key role in neuronal circuit and synaptic maturation in the developing brain. In the healthy adult, however, their role is less clear: microglial hyperactivation in adults can be detrimental to memory due to excessive synaptic pruning, yet learning and memory can also be...

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Detalles Bibliográficos
Autores principales: De Luca, Simone N., Soch, Alita, Sominsky, Luba, Nguyen, Thai-Xinh, Bosakhar, Abdulhameed, Spencer, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006153/
https://www.ncbi.nlm.nih.gov/pubmed/32028971
http://dx.doi.org/10.1186/s12974-020-1729-4