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The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein

BACKGROUND: The Ecotropic viral integration site 5 (Evi5) is recognized as a potential oncogene and a cell cycle regulator. Evi5 regulates the abundance of Emi1, an inhibitor of the anaphase-promoting complex/cyclosome, to govern mitotic fidelity. Evi5 has been shown to be dysregulated in several ca...

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Detalles Bibliográficos
Autores principales: Mao, Cheng-Gang, Zhou, Xiao-Chun, Jiang, Yi-Dao, Wan, Li-Jia, Tao, Ze-Zhang, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006165/
https://www.ncbi.nlm.nih.gov/pubmed/32047362
http://dx.doi.org/10.1186/s12935-020-1127-0