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Buprenorphine to reverse respiratory depression from methadone overdose in opioid-dependent patients: a prospective randomized trial

BACKGROUND: Naloxone is the usual drug used in opioid-induced respiratory depression but it has a short half-life, precipitates withdrawal in dependent patients, and thus for persistent reversal of long-acting opioids has to be given by titrated doses and infusions. The partial agonist buprenorphine...

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Detalles Bibliográficos
Autores principales: Zamani, Nasim, Buckley, Nicholas A., Hassanian-Moghaddam, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006192/
https://www.ncbi.nlm.nih.gov/pubmed/32033582
http://dx.doi.org/10.1186/s13054-020-2740-y