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Aryl hydrocarbon receptor signals attenuate lung fibrosis in the bleomycin-induced mouse model for pulmonary fibrosis through increase of regulatory T cells

BACKGROUND: Interstitial lung disease (ILD) is a serious complication of connective tissue diseases (CTDs). Although immune dysregulation triggered by genetic and environmental factors is thought to provoke inflammation and subsequent fibrosis, precise mechanisms of these processes remain unclear. R...

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Detalles Bibliográficos
Autores principales: Takei, Hiroshi, Yasuoka, Hidekata, Yoshimoto, Keiko, Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006193/
https://www.ncbi.nlm.nih.gov/pubmed/32033616
http://dx.doi.org/10.1186/s13075-020-2112-7