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Differential significance of molecular subtypes which were classified into EGFR exon 19 deletion on the first line afatinib monotherapy

BACKGROUND: Epidermal growth factor receptor (EGFR)-sensitizing mutation, exon 19 deletion consists of several molecular variants. Influences of these variants on clinical response to EGFR tyrosine kinase inhibitors remain elusive. METHODS: West Japan Oncology Group 8114LTR is a prospective, multi-i...

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Detalles Bibliográficos
Autores principales: Tokudome, Nahomi, Koh, Yasuhiro, Akamatsu, Hiroaki, Fujimoto, Daichi, Okamoto, Isamu, Nakagawa, Kazuhiko, Hida, Toyoaki, Imamura, Fumio, Morita, Satoshi, Yamamoto, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006223/
https://www.ncbi.nlm.nih.gov/pubmed/32028909
http://dx.doi.org/10.1186/s12885-020-6593-1