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Apoptosis Induction by Menadione in Human Promyelocytic Leukemia HL-60 Cells

Cell death induced by menadione (vitamin K-3,2-methyl-1,4-naphthoquinone) has been investigated in human promyelocytic leukemia HL-60 cells. Menadione was found to induce both apoptosis and necrosis in HL-60 cells. Low concentration (1~50 µM) of menadione induced apoptotic cell death, which was demo...

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Detalles Bibliográficos
Autores principales: Sa, Duck-Jin, Lee, Eun-Jee, Yoo, Byung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006246/
https://www.ncbi.nlm.nih.gov/pubmed/32038828
http://dx.doi.org/10.5487/TR.2009.25.3.113