Effects of Oral Rutaecarpine on the Pharmacokinetics of Intravenous Chlorzoxazone in Rats

It has been reported that hepatic microsomal cytochrome P450 (CYP) 2E1 is responsible for the metabolism of chlorzoxazone (CZX) to 6-hydroxychlorzoxazone. The present study was undertaken to assess the possible interaction of rutaecarpine, an alkaloid originally isolated from the unripe fruit of Evo...

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Detalles Bibliográficos
Autores principales: Bista, Sudeep R., Lee, Sang Kyu, Thapa, Dinesh, Kang, Mi Jeong, Seo, Young Min, Kim, Ju Hyun, Kim, Dong Hyeon, Jahng, Yurngdong, Kim, Jung Ae, Jeong, Tae Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006287/
https://www.ncbi.nlm.nih.gov/pubmed/32038795
http://dx.doi.org/10.5487/TR.2008.24.3.195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006287/
https://www.ncbi.nlm.nih.gov/pubmed/32038795
http://dx.doi.org/10.5487/TR.2008.24.3.195

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