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Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells

Alpha-synuclein (αSyn(Agg)) are pathological hallmarks of Parkinson's disease (PD) and other synucleinopathies that induce microglial activation and immune-mediated neurotoxicity, but the molecular mechanisms of αSyn(Agg)-induced immune activation are poorly defined. We performed quantitative p...

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Detalles Bibliográficos
Autores principales: Sarkar, Souvarish, Dammer, Eric B., Malovic, Emir, Olsen, Abby L., Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Oliver, Danielle L., Duong, Duc, Joers, Valerie, Seyfried, Nicholas, Huang, Meixiang, Kukar, Thomas, Tansey, Malú G., Kanthasamy, Anumantha G., Rangaraju, Srikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006296/
https://www.ncbi.nlm.nih.gov/pubmed/32082315
http://dx.doi.org/10.3389/fimmu.2020.00033