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Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells
Alpha-synuclein (αSyn(Agg)) are pathological hallmarks of Parkinson's disease (PD) and other synucleinopathies that induce microglial activation and immune-mediated neurotoxicity, but the molecular mechanisms of αSyn(Agg)-induced immune activation are poorly defined. We performed quantitative p...
Autores principales: | Sarkar, Souvarish, Dammer, Eric B., Malovic, Emir, Olsen, Abby L., Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Oliver, Danielle L., Duong, Duc, Joers, Valerie, Seyfried, Nicholas, Huang, Meixiang, Kukar, Thomas, Tansey, Malú G., Kanthasamy, Anumantha G., Rangaraju, Srikant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006296/ https://www.ncbi.nlm.nih.gov/pubmed/32082315 http://dx.doi.org/10.3389/fimmu.2020.00033 |
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