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Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo

Background: Hemithioindigo is a promising molecular photoswitch that has only recently been applied as a photoswitchable pharmacophore for control over bioactivity in cellulo. Uniquely, in contrast to other photoswitches that have been applied to biology, the pseudosymmetric hemithioindigo scaffold...

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Detalles Bibliográficos
Autores principales: Sailer, Alexander, Ermer, Franziska, Kraus, Yvonne, Bingham, Rebekkah, Lutter, Ferdinand H, Ahlfeld, Julia, Thorn-Seshold, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006478/
https://www.ncbi.nlm.nih.gov/pubmed/32082431
http://dx.doi.org/10.3762/bjoc.16.14