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Rapid, two-pot procedure for the synthesis of dihydropyridinones; total synthesis of aza-goniothalamin

A fast, protecting-group-free synthesis of dihydropyridinones has been developed. Starting from commercially available aldehydes, a novel one-pot amidoallylation gave access to diene compounds in good yields. Ring-closing metathesis conditions were then employed to produce the target dihydropyridino...

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Detalles Bibliográficos
Autores principales: Cogswell, Thomas J, Donald, Craig S, Marquez, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006497/
https://www.ncbi.nlm.nih.gov/pubmed/32082432
http://dx.doi.org/10.3762/bjoc.16.15