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Identification and validation of key modules and hub genes associated with the pathological stage of oral squamous cell carcinoma by weighted gene co-expression network analysis

BACKGROUND: Oral squamous cell carcinoma (OSCC) is a major lethal malignant cancer of the head and neck region, yet its molecular mechanisms of tumourigenesis are still unclear. PATIENTS AND METHODS: We performed weighted gene co-expression network analysis (WGCNA) on RNA-sequencing data with clinic...

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Detalles Bibliográficos
Autores principales: Hu, Xuegang, Sun, Guanwen, Shi, Zhiqiang, Ni, Hui, Jiang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006519/
https://www.ncbi.nlm.nih.gov/pubmed/32117620
http://dx.doi.org/10.7717/peerj.8505